1Department of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Augusta, GA.

2Department of Population Health Science: Biostats & Data Science, Medical College of Georgia, Augusta, GA.

3Department of Pharmacy, Loyola University Medical Center, Maywood, IL.

4Department of Pharmacy Services, Princeton Baptist Medical Center, Birmingham, AL.

5Department of Pharmacy, Guthrie Robert Packer Hospital, Sayre, PA.

6Department of Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA.

7Department of Pharmacy, Medical University of South Carolina, Charleston, SC.

8Department of Pharmacy, Wellstar Kennestone Regional Medical Center, Marietta, GA.

9Department of Pharmacy, Columbia University Irving Medical Center, NewYork-Presbyterian Hospital, New York, NY.

10Department of Pharmacy, University of Kentucky College of Pharmacy, Lexington, KY.

11Department of Pharmacy, The University of Tennessee Health Science Center College of Pharmacy, Knoxville, TN.

12Department of Pharmacy, University of Maryland School of Pharmacy, Baltimore, MD.

13Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX.

14Department of Pharmacy, Highland Hospital, Alameda Health System, Oakland, CA.

15Department of Pharmacy, Critical Care/Emergency Medicine Clinical Pharmacy Specialist, AMITA Health Saints Mary and Elizabeth Medical Center, Chicago, IL.

16Department of Pharmacy, Lakeland Regional Health, Lakeland, FL.

17Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, GA.

18Department of Pharmacy, John H. Stroger, Jr Hospital of Cook County, Chicago, IL.

19Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Phoenix, AZ.

20Department of Pharmacy, Cleveland Clinic, Cleveland, OH.

21Department of Pharmacy, Advocate Christ Medical Center, Oak Lawn, IL.

22Department of Pharmacy, LRGHealthcare, Laconia, NH.

23Department of Pharmacy, Henry Ford Hospital, Detroit, MI.

24Department of Pharmacy, St. Joseph’s Hospital and Medical Center, Phoenix, AZ.

25Sarasota Memorial Hospital, Sarasota, FL.

*See also p. 1399.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).

Dr. Newsome has received research funding through the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Numbers UL1TR002378 and KL2TR002381. Dr. Rech’s institution received funding from Spero Pharmaceuticals; she received funding from Harm Reduction Therapeutics. Dr. DePriest received funding from Baxter. Dr. Flannery’s institution received funding from the National Institute of Diabetes and Digestive and Kidney Diseases, the American Society of Nephrology, and La Jolla Pharmaceutical Company. The remaining authors have disclosed that they do not have any potential conflicts of interest.

Members of the MRC-ICU Investigator Team are listed in Appendix 1 (https://links.lww.com/CCM/H140).

For information regarding this article, E-mail: [email protected]